Mieap suppresses murine intestinal tumor via its mitochondrial quality control

Mieap, a novel p53-inducible protein, plays a key role in maintaining healthy mitochondria in various pathophysiological states. Here, we show that Mieap deficiency in Apc(Min/+) mice is strikingly associated with the malignant progression of murine intestinal tumors. To understand the role that Mie...

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Detalles Bibliográficos
Autores principales: Tsuneki, Masayuki, Nakamura, Yasuyuki, Kinjo, Takao, Nakanishi, Ruri, Arakawa, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516962/
https://www.ncbi.nlm.nih.gov/pubmed/26216032
http://dx.doi.org/10.1038/srep12472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516962/
https://www.ncbi.nlm.nih.gov/pubmed/26216032
http://dx.doi.org/10.1038/srep12472

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