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Transactivation of human osteoprotegerin promoter by GATA-3

Osteoprotegerin (OPG) is a key regulator of bone remodeling. Mutations in OPG are involved in a variety of human diseases. We have shown that cochlear spiral ganglion cells secrete OPG at high levels and lack of OPG causes sensorineural hearing loss in addition to the previously described conductive...

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Detalles Bibliográficos
Autores principales: Kao, Shyan-Yuan, Stankovic, Konstantina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516985/
https://www.ncbi.nlm.nih.gov/pubmed/26216189
http://dx.doi.org/10.1038/srep12479