Pulmonary Inflammation Impacts on CYP1A1-Mediated Respiratory Tract DNA Damage Induced by the Carcinogenic Air Pollutant Benzo[a]pyrene

Pulmonary inflammation can contribute to the development of lung cancer in humans. We investigated whether pulmonary inflammation alters the genotoxicity of polycyclic aromatic hydrocarbons (PAHs) in the lungs of mice and what mechanisms are involved. To model nonallergic acute inflammation, mice we...

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Detalles Bibliográficos
Autores principales: Arlt, Volker M., Krais, Annette M., Godschalk, Roger W., Riffo-Vasquez, Yanira, Mrizova, Iveta, Roufosse, Candice A., Corbin, Charmaine, Shi, Quan, Frei, Eva, Stiborova, Marie, van Schooten, Frederik-Jan, Phillips, David H., Spina, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Benzo[a]pyrene and Respiratory Tract DNA Damage
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517052/
https://www.ncbi.nlm.nih.gov/pubmed/25911668
http://dx.doi.org/10.1093/toxsci/kfv086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517052/
https://www.ncbi.nlm.nih.gov/pubmed/25911668
http://dx.doi.org/10.1093/toxsci/kfv086

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