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Rapid parallel measurements of macroautophagy and mitophagy in mammalian cells using a single fluorescent biosensor

Mitochondrial dysfunction is implicated in many human diseases and occurs in normal aging. Mitochondrial health is maintained through organelle biogenesis and repair or turnover of existing mitochondria. Mitochondrial turnover is principally mediated by mitophagy, the trafficking of damaged mitochon...

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Detalles Bibliográficos
Autores principales: Sargsyan, A., Cai, J., Fandino, L. B., Labasky, M. E., Forostyan, T., Colosimo, L. K., Thompson, S. J., Graham, T. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517063/
https://www.ncbi.nlm.nih.gov/pubmed/26215030
http://dx.doi.org/10.1038/srep12397