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Rapid parallel measurements of macroautophagy and mitophagy in mammalian cells using a single fluorescent biosensor
Mitochondrial dysfunction is implicated in many human diseases and occurs in normal aging. Mitochondrial health is maintained through organelle biogenesis and repair or turnover of existing mitochondria. Mitochondrial turnover is principally mediated by mitophagy, the trafficking of damaged mitochon...
Autores principales: | Sargsyan, A., Cai, J., Fandino, L. B., Labasky, M. E., Forostyan, T., Colosimo, L. K., Thompson, S. J., Graham, T. E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517063/ https://www.ncbi.nlm.nih.gov/pubmed/26215030 http://dx.doi.org/10.1038/srep12397 |
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