Stereodivergent Organocatalytic Intramolecular Michael Addition/Lactonization for the Asymmetric Synthesis of Substituted Dihydrobenzofurans and Tetrahydrofurans

A stereodivergent asymmetric Lewis base catalyzed Michael addition/lactonization of enone acids into substituted dihydrobenzofuran and tetrahydrofuran derivatives is reported. Commercially available (S)-(−)-tetramisole hydrochloride gives products with high syn diastereoselectivity in excellent enan...

Descripción completa

Detalles Bibliográficos
Autores principales: Belmessieri, Dorine, de la Houpliere, Alix, Calder, Ewen D D, Taylor, James E, Smith, Andrew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2014
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517160/
https://www.ncbi.nlm.nih.gov/pubmed/24989672
http://dx.doi.org/10.1002/chem.201402684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517160/
https://www.ncbi.nlm.nih.gov/pubmed/24989672
http://dx.doi.org/10.1002/chem.201402684

Ejemplares similares