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Different gap junction-propagated effects on cisplatin transfer result in opposite responses to cisplatin in normal cells versus tumor cells

Previous work has shown that gap junction intercellular communication (GJIC) enhances cisplatin (Pt) toxicity in testicular tumor cells but decreases it in non-tumor testicular cells. In this study, these different GJIC-propagated effects were demonstrated in tumor versus non-tumor cells from other...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Tao, Liang, Fan, Lixia, Peng, Yuexia, Yang, Kefan, Zhao, Yifan, Song, Qi, Wang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517168/
https://www.ncbi.nlm.nih.gov/pubmed/26215139
http://dx.doi.org/10.1038/srep12563