Genomic approaches to identifying targets for treating β hemoglobinopathies

Sickle cell disease and β thalassemia are common severe diseases with little effective pathophysiologically-based treatment. Their phenotypic heterogeneity prompted genomic approaches to identify modifiers that ultimately might be exploited therapeutically. Fetal hemoglobin (HbF) is the major modula...

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Detalles Bibliográficos
Autores principales: Ngo, Duyen A., Steinberg, Martin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517356/
https://www.ncbi.nlm.nih.gov/pubmed/26215470
http://dx.doi.org/10.1186/s12920-015-0120-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517356/
https://www.ncbi.nlm.nih.gov/pubmed/26215470
http://dx.doi.org/10.1186/s12920-015-0120-2

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