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Human xylosyltransferases – mediators of arthrofibrosis? New pathomechanistic insights into arthrofibrotic remodeling after knee replacement therapy

Total knee replacement (TKR) is a common therapeutic option to restore joint functionality in chronic inflammatory joint diseases. Subsequent arthrofibrotic remodeling occurs in 10%, but the underlying pathomechanisms remain unclear. We evaluated the association of xylosyltransferases (XT), fibrotic...

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Detalles Bibliográficos
Autores principales: Faust, Isabel, Traut, Philipp, Nolting, Frank, Petschallies, Jan, Neumann, Elena, Kunisch, Elke, Kuhn, Joachim, Knabbe, Cornelius, Hendig, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517395/
https://www.ncbi.nlm.nih.gov/pubmed/26219087
http://dx.doi.org/10.1038/srep12537