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The Notch-mediated hyperplasia circuitry in Drosophila reveals a Src-JNK signaling axis

Notch signaling controls a wide range of cell fate decisions during development and disease via synergistic interactions with other signaling pathways. Here, through a genome-wide genetic screen in Drosophila, we uncover a highly complex Notch-dependent genetic circuitry that profoundly affects prol...

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Detalles Bibliográficos
Autores principales: Ho, Diana M, Pallavi, SK, Artavanis-Tsakonas, Spyros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517436/
https://www.ncbi.nlm.nih.gov/pubmed/26222204
http://dx.doi.org/10.7554/eLife.05996