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The Notch-mediated hyperplasia circuitry in Drosophila reveals a Src-JNK signaling axis
Notch signaling controls a wide range of cell fate decisions during development and disease via synergistic interactions with other signaling pathways. Here, through a genome-wide genetic screen in Drosophila, we uncover a highly complex Notch-dependent genetic circuitry that profoundly affects prol...
Autores principales: | Ho, Diana M, Pallavi, SK, Artavanis-Tsakonas, Spyros |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517436/ https://www.ncbi.nlm.nih.gov/pubmed/26222204 http://dx.doi.org/10.7554/eLife.05996 |
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