LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling

The liver X receptors (LXRs) are transcriptional regulators of lipid homeostasis that also have potent anti-inflammatory effects. The molecular basis for their anti-inflammatory effects is incompletely understood, but has been proposed to involve the indirect tethering of LXRs to inflammatory gene p...

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Detalles Bibliográficos
Autores principales: Ito, Ayaka, Hong, Cynthia, Rong, Xin, Zhu, Xuewei, Tarling, Elizabeth J, Hedde, Per Niklas, Gratton, Enrico, Parks, John, Tontonoz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517437/
https://www.ncbi.nlm.nih.gov/pubmed/26173179
http://dx.doi.org/10.7554/eLife.08009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517437/
https://www.ncbi.nlm.nih.gov/pubmed/26173179
http://dx.doi.org/10.7554/eLife.08009

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