Age-associated reduction of cell spreading induces mitochondrial DNA common deletion by oxidative stress in human skin dermal fibroblasts: implication for human skin connective tissue aging

BACKGROUND: Reduced cell spreading is a prominent feature of aged dermal fibroblasts in human skin in vivo. Mitochondrial DNA (mtDNA) common deletion has been reported to play a role in the human aging process, however the relationship between age-related reduced cell spreading and mtDNA common dele...

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Detalles Bibliográficos
Autores principales: Quan, Chunji, Cho, Moon Kyun, Perry, Daniel, Quan, Taihao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517525/
https://www.ncbi.nlm.nih.gov/pubmed/26215577
http://dx.doi.org/10.1186/s12929-015-0167-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517525/
https://www.ncbi.nlm.nih.gov/pubmed/26215577
http://dx.doi.org/10.1186/s12929-015-0167-6

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