Improved diagnostics targeting c-MET in non-small cell lung cancer: expression, amplification and activation?

BACKGROUND: Several c-MET targeting inhibitory molecules have already shown promising results in the treatment of patients with Non-small Cell Lung Cancer (NSCLC). Combination of EGFR- and c-MET-specific molecules may overcome EGFR tyrosine kinase inhibitor (TKI) resistance. The aim of this study wa...

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Detalles Bibliográficos
Autores principales: Watermann, I., Schmitt, B., Stellmacher, F., Müller, J., Gaber, R., Kugler, Ch., Reinmuth, N., Huber, R. M., Thomas, M., Zabel, P., Rabe, K. F., Jonigk, D., Warth, A., Vollmer, E., Reck, M., Goldmann, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517562/
https://www.ncbi.nlm.nih.gov/pubmed/26215852
http://dx.doi.org/10.1186/s13000-015-0362-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517562/
https://www.ncbi.nlm.nih.gov/pubmed/26215852
http://dx.doi.org/10.1186/s13000-015-0362-5

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