Pharmacological mechanism underlying anti-inflammatory properties of two structurally divergent coumarins through the inhibition of pro-inflammatory enzymes and cytokines

BACKGROUND: The aim of the present study is to investigate the effects of two structurally divergent coumarins, calipteryxin (1) and (3’S,4’S)-3’,4’-disenecioyloxy-3’,4’-dihydroseselin (2) from Seseli recinosum, in lipopolysaccharide (LPS)-stimulated murine macrophages. METHODS: The nitrite producti...

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Detalles Bibliográficos
Autores principales: Khan, Salman, Shehzad, Omer, Cheng, Mao-Sheng, Li, Rui-Juan, Kim, Yeong Shik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517569/
https://www.ncbi.nlm.nih.gov/pubmed/26221081
http://dx.doi.org/10.1186/s12950-015-0087-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517569/
https://www.ncbi.nlm.nih.gov/pubmed/26221081
http://dx.doi.org/10.1186/s12950-015-0087-y

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