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Pharmacological mechanism underlying anti-inflammatory properties of two structurally divergent coumarins through the inhibition of pro-inflammatory enzymes and cytokines
BACKGROUND: The aim of the present study is to investigate the effects of two structurally divergent coumarins, calipteryxin (1) and (3’S,4’S)-3’,4’-disenecioyloxy-3’,4’-dihydroseselin (2) from Seseli recinosum, in lipopolysaccharide (LPS)-stimulated murine macrophages. METHODS: The nitrite producti...
Autores principales: | Khan, Salman, Shehzad, Omer, Cheng, Mao-Sheng, Li, Rui-Juan, Kim, Yeong Shik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517569/ https://www.ncbi.nlm.nih.gov/pubmed/26221081 http://dx.doi.org/10.1186/s12950-015-0087-y |
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