Functionalized PHB granules provide the basis for the efficient side-chain cleavage of cholesterol and analogs in recombinant Bacillus megaterium

BACKGROUND: Cholesterol, the precursor of all steroid hormones, is the most abundant steroid in vertebrates and exhibits highly hydrophobic properties, rendering it a difficult substrate for aqueous microbial biotransformations. In the present study, we developed a Bacillus megaterium based whole-ce...

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Detalles Bibliográficos
Autores principales: Gerber, Adrian, Kleser, Michael, Biedendieck, Rebekka, Bernhardt, Rita, Hannemann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517628/
https://www.ncbi.nlm.nih.gov/pubmed/26215140
http://dx.doi.org/10.1186/s12934-015-0300-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517628/
https://www.ncbi.nlm.nih.gov/pubmed/26215140
http://dx.doi.org/10.1186/s12934-015-0300-y

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