Partial inhibition of the ubiquitin–proteasome system ameliorates cardiac dysfunction following ischemia–reperfusion in the presence of high glucose

BACKGROUND: Acute hyperglycemia co-presenting with myocardial infarction (in diabetic and non-diabetic individuals) is often associated with a poor prognosis. Although acute hyperglycemia induces oxidative stress that can lead to dysregulation of the ubiquitin–proteasome system (UPS), it is unclear...

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Detalles Bibliográficos
Autores principales: Adams, Buin, Mapanga, Rudo F, Essop, M Faadiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517635/
https://www.ncbi.nlm.nih.gov/pubmed/26216448
http://dx.doi.org/10.1186/s12933-015-0258-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517635/
https://www.ncbi.nlm.nih.gov/pubmed/26216448
http://dx.doi.org/10.1186/s12933-015-0258-4

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