The Demethylase Activity of FTO (Fat Mass and Obesity Associated Protein) Is Required for Preadipocyte Differentiation

FTO (fat mass and obesity associated gene) was genetically identified to be associated with body mass index (BMI), presumably through functional regulation of energy homeostasis. However, the cellular and molecular mechanisms by which FTO functions remain largely unknown. Using 3T3-L1 preadipocyte a...

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Detalles Bibliográficos
Autores principales: Zhang, Meizi, Zhang, Ying, Ma, Jun, Guo, Feima, Cao, Qian, Zhang, Yu, Zhou, Bin, Chai, Jijie, Zhao, Wenqing, Zhao, Renbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517749/
https://www.ncbi.nlm.nih.gov/pubmed/26218273
http://dx.doi.org/10.1371/journal.pone.0133788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517749/
https://www.ncbi.nlm.nih.gov/pubmed/26218273
http://dx.doi.org/10.1371/journal.pone.0133788

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