Partially Evoked Epithelial-Mesenchymal Transition (EMT) Is Associated with Increased TGFβ Signaling within Lesional Scleroderma Skin

The origin of myofibroblasts in fibrotic conditions remains unknown and in systemic sclerosis (SSc) it has been proposed that activation of local fibroblasts, trans-differentiation of perivascular or vascular cells, recruitment of fibrocyte progenitors, or epithelial to mesenchymal transition (EMT)...

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Detalles Bibliográficos
Autores principales: Nikitorowicz-Buniak, Joanna, Denton, Christopher P., Abraham, David, Stratton, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517793/
https://www.ncbi.nlm.nih.gov/pubmed/26217927
http://dx.doi.org/10.1371/journal.pone.0134092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517793/
https://www.ncbi.nlm.nih.gov/pubmed/26217927
http://dx.doi.org/10.1371/journal.pone.0134092

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