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Targeted Deletion of Btg1 and Btg2 Results in Homeotic Transformation of the Axial Skeleton

Btg1 and Btg2 encode highly homologous proteins that are broadly expressed in different cell lineages, and have been implicated in different types of cancer. Btg1 and Btg2 have been shown to modulate the function of different transcriptional regulators, including Hox and Smad transcription factors....

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Detalles Bibliográficos
Autores principales: Tijchon, Esther, van Ingen Schenau, Dorette, van Opzeeland, Fred, Tirone, Felice, Hoogerbrugge, Peter M., Van Leeuwen, Frank N., Scheijen, Blanca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517811/
https://www.ncbi.nlm.nih.gov/pubmed/26218146
http://dx.doi.org/10.1371/journal.pone.0131481