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Lipopolysaccharide Exposure Induces Maternal Hypozincemia, and Prenatal Zinc Treatment Prevents Autistic-Like Behaviors and Disturbances in the Striatal Dopaminergic and mTOR Systems of Offspring

Autism is characterized by social deficits, repetitive behaviors, and cognitive inflexibility. The risk factors appear to include genetic and environmental conditions, such as prenatal infections and maternal dietary factors. Previous investigations by our group have demonstrated that prenatal expos...

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Detalles Bibliográficos
Autores principales: Kirsten, Thiago Berti, Chaves-Kirsten, Gabriela P., Bernardes, Suene, Scavone, Cristoforo, Sarkis, Jorge E., Bernardi, Maria Martha, Felicio, Luciano F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517817/
https://www.ncbi.nlm.nih.gov/pubmed/26218250
http://dx.doi.org/10.1371/journal.pone.0134565