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Flux Balance Analysis with Objective Function Defined by Proteomics Data—Metabolism of Mycobacterium tuberculosis Exposed to Mefloquine

We present a study of the metabolism of the Mycobacterium tuberculosis after exposure to antibiotics using proteomics data and flux balance analysis (FBA). The use of FBA to study prokaryotic organisms is well-established and allows insights into the metabolic pathways chosen by the organisms under...

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Detalles Bibliográficos
Autores principales: Montezano, Daniel, Meek, Laura, Gupta, Rashmi, Bermudez, Luiz E., Bermudez, José C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517854/
https://www.ncbi.nlm.nih.gov/pubmed/26218987
http://dx.doi.org/10.1371/journal.pone.0134014