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Flux Balance Analysis with Objective Function Defined by Proteomics Data—Metabolism of Mycobacterium tuberculosis Exposed to Mefloquine
We present a study of the metabolism of the Mycobacterium tuberculosis after exposure to antibiotics using proteomics data and flux balance analysis (FBA). The use of FBA to study prokaryotic organisms is well-established and allows insights into the metabolic pathways chosen by the organisms under...
Autores principales: | Montezano, Daniel, Meek, Laura, Gupta, Rashmi, Bermudez, Luiz E., Bermudez, José C. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517854/ https://www.ncbi.nlm.nih.gov/pubmed/26218987 http://dx.doi.org/10.1371/journal.pone.0134014 |
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