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Opposing Effects of cAMP and T259 Phosphorylation on Plasma Membrane Diffusion of the Water Channel Aquaporin-5 in Madin-Darby Canine Kidney Cells

Aquaporin-5 (AQP5) facilitates passive water transport in glandular epithelia in response to secretory stimuli via intracellular pathways involving calcium release, cAMP and protein kinase A (PKA). In epithelial plasma membranes, AQP5 may be acutely regulated to facilitate water transport in respons...

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Detalles Bibliográficos
Autores principales: Koffman, Jennifer S., Arnspang, Eva C., Marlar, Saw, Nejsum, Lene N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517861/
https://www.ncbi.nlm.nih.gov/pubmed/26218429
http://dx.doi.org/10.1371/journal.pone.0133324