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Uridylation of RNA Hairpins by Tailor Confines the Emergence of MicroRNAs in Drosophila

Uridylation of RNA species represents an emerging theme in post-transcriptional gene regulation. In the microRNA pathway, such modifications regulate small RNA biogenesis and stability in plants, worms, and mammals. Here, we report Tailor, an uridylyltransferase that is required for the majority of...

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Detalles Bibliográficos
Autores principales: Reimão-Pinto, Madalena M., Ignatova, Valentina, Burkard, Thomas R., Hung, Jui-Hung, Manzenreither, Raphael A., Sowemimo, Ivica, Herzog, Veronika A., Reichholf, Brian, Fariña-Lopez, Sara, Ameres, Stefan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518039/
https://www.ncbi.nlm.nih.gov/pubmed/26145176
http://dx.doi.org/10.1016/j.molcel.2015.05.033