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Enhanced Production of Insulin-like Growth Factor I Protein in Escherichia coli by Optimization of Five Key Factors

Human insulin-like growth factor I (hIGF-I) is a kind of growth factor with clinical significance in medicine. Up to now, E. coli expression system has been widely used as a host to produce rhIGF-1 with high yields. Batch cultures as non-continuous fermentations were carried out to overproduce rhIGF-...

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Detalles Bibliográficos
Autores principales: Ranjbari, Javad, Babaeipour, Valiollah, Vahidi, Hossein, Moghimi, Hamidreza, Mofid, Mohammad Reza, Namvaran, Mohammad Mehdi, Jafari, Sevda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518120/
https://www.ncbi.nlm.nih.gov/pubmed/26330880