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Toll-Like Receptor 9 Inactivation Alleviated Atherosclerotic Progression and Inhibited Macrophage Polarized to M1 Phenotype in ApoE(−/−) Mice

Objective. Toll-like receptor 9 (TLR9) is involved in many inflammatory diseases, but its role in atherosclerosis remains controversial. This study aimed to investigate the role of TLR9 in atherosclerosis development and macrophage polarization. Methods. ApoE(−/−) mice were treated with vehicle or I...

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Detalles Bibliográficos
Autores principales: Ma, Chunmei, Ouyang, Qiufang, Huang, Ziyang, Chen, Xiaoqing, Lin, Ye, Hu, Weiping, Lin, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518170/
https://www.ncbi.nlm.nih.gov/pubmed/26257462
http://dx.doi.org/10.1155/2015/909572