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Toll-Like Receptor 9 Inactivation Alleviated Atherosclerotic Progression and Inhibited Macrophage Polarized to M1 Phenotype in ApoE(−/−) Mice
Objective. Toll-like receptor 9 (TLR9) is involved in many inflammatory diseases, but its role in atherosclerosis remains controversial. This study aimed to investigate the role of TLR9 in atherosclerosis development and macrophage polarization. Methods. ApoE(−/−) mice were treated with vehicle or I...
Autores principales: | Ma, Chunmei, Ouyang, Qiufang, Huang, Ziyang, Chen, Xiaoqing, Lin, Ye, Hu, Weiping, Lin, Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518170/ https://www.ncbi.nlm.nih.gov/pubmed/26257462 http://dx.doi.org/10.1155/2015/909572 |
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