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Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1

Acute lung injury (ALI) is a severe inflammatory disease for which no specific treatment exists. As glucocorticoids have potent immunosuppressive effects, their application in ALI is currently being tested in clinical trials. However, the benefits of this type of regimen remain unclear. Here we iden...

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Detalles Bibliográficos
Autores principales: Vettorazzi, Sabine, Bode, Constantin, Dejager, Lien, Frappart, Lucien, Shelest, Ekaterina, Klaßen, Carina, Tasdogan, Alpaslan, Reichardt, Holger M., Libert, Claude, Schneider, Marion, Weih, Falk, Henriette Uhlenhaut, N., David, Jean-Pierre, Gräler, Markus, Kleiman, Anna, Tuckermann, Jan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518295/
https://www.ncbi.nlm.nih.gov/pubmed/26183376
http://dx.doi.org/10.1038/ncomms8796