Three missense variants of metabolic syndrome-related genes are associated with alpha-1 antitrypsin levels

Alpha-1 antitrypsin (AAT) encoded by SERPINA1 is an acute-phase inflammation marker, and AAT deficiency (AATD) is known as one of the common genetic disorders in European populations. However, no genetic determinants to AAT levels apart from the SERPINA gene clusters have been identified to date. He...

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Detalles Bibliográficos
Autores principales: Setoh, Kazuya, Terao, Chikashi, Muro, Shigeo, Kawaguchi, Takahisa, Tabara, Yasuharu, Takahashi, Meiko, Nakayama, Takeo, Kosugi, Shinji, Sekine, Akihiro, Yamada, Ryo, Mishima, Michiaki, Matsuda, Fumihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518310/
https://www.ncbi.nlm.nih.gov/pubmed/26174136
http://dx.doi.org/10.1038/ncomms8754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518310/
https://www.ncbi.nlm.nih.gov/pubmed/26174136
http://dx.doi.org/10.1038/ncomms8754

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