An autoinhibitory mechanism modulates MAVS activity in antiviral innate immune response

In response to virus infection, RIG-I senses viral RNA and activates the adaptor protein MAVS, which then forms prion-like filaments and stimulates a specific signalling pathway leading to type I interferon production to restrict virus proliferation. However, the mechanisms by which MAVS activity is...

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Detalles Bibliográficos
Autores principales: Shi, Yuheng, Yuan, Bofeng, Qi, Nan, Zhu, Wenting, Su, Jingru, Li, Xiaoyan, Qi, Peipei, Zhang, Dan, Hou, Fajian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518314/
https://www.ncbi.nlm.nih.gov/pubmed/26183716
http://dx.doi.org/10.1038/ncomms8811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518314/
https://www.ncbi.nlm.nih.gov/pubmed/26183716
http://dx.doi.org/10.1038/ncomms8811

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