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An actin-dependent spindle position checkpoint ensures the asymmetric division in mouse oocytes

Faithful chromosome segregation, during meiosis, is of critical importance to prevent aneuploidy in the resulting embryo. In mammalian oocytes, the segregation of homologous chromosomes takes place with the spindle located at the cell's periphery. The spindle is often assembled close to the cen...

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Detalles Bibliográficos
Autores principales: Metchat, Aïcha, Eguren, Manuel, Hossain, Julius M., Politi, Antonio Z., Huet, Sébastien, Ellenberg, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518315/
https://www.ncbi.nlm.nih.gov/pubmed/26174204
http://dx.doi.org/10.1038/ncomms8784