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An actin-dependent spindle position checkpoint ensures the asymmetric division in mouse oocytes
Faithful chromosome segregation, during meiosis, is of critical importance to prevent aneuploidy in the resulting embryo. In mammalian oocytes, the segregation of homologous chromosomes takes place with the spindle located at the cell's periphery. The spindle is often assembled close to the cen...
Autores principales: | Metchat, Aïcha, Eguren, Manuel, Hossain, Julius M., Politi, Antonio Z., Huet, Sébastien, Ellenberg, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518315/ https://www.ncbi.nlm.nih.gov/pubmed/26174204 http://dx.doi.org/10.1038/ncomms8784 |
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