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A delicate balance: role of MMP-9 in brain development and pathophysiology of neurodevelopmental disorders

The extracellular matrix (ECM) is a critical regulator of neural network development and plasticity. As neuronal circuits develop, the ECM stabilizes synaptic contacts, while its cleavage has both permissive and active roles in the regulation of plasticity. Matrix metalloproteinase 9 (MMP-9) is a me...

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Detalles Bibliográficos
Autores principales: Reinhard, Sarah M., Razak, Khaleel, Ethell, Iryna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518323/
https://www.ncbi.nlm.nih.gov/pubmed/26283917
http://dx.doi.org/10.3389/fncel.2015.00280