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A delicate balance: role of MMP-9 in brain development and pathophysiology of neurodevelopmental disorders
The extracellular matrix (ECM) is a critical regulator of neural network development and plasticity. As neuronal circuits develop, the ECM stabilizes synaptic contacts, while its cleavage has both permissive and active roles in the regulation of plasticity. Matrix metalloproteinase 9 (MMP-9) is a me...
Autores principales: | Reinhard, Sarah M., Razak, Khaleel, Ethell, Iryna M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518323/ https://www.ncbi.nlm.nih.gov/pubmed/26283917 http://dx.doi.org/10.3389/fncel.2015.00280 |
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