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Voltage-gated sodium channels and cancer: is excitability their primary role?

Voltage-gated sodium channels (Na(V)) are molecular characteristics of excitable cells. Their activation, triggered by membrane depolarization, generates transient sodium currents that initiate action potentials in neurons and muscle cells. Sodium currents were discovered by Hodgkin and Huxley using...

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Detalles Bibliográficos
Autores principales: Roger, Sébastien, Gillet, Ludovic, Le Guennec, Jean-Yves, Besson, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518325/
https://www.ncbi.nlm.nih.gov/pubmed/26283962
http://dx.doi.org/10.3389/fphar.2015.00152