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BAX/BCL-2 mRNA and protein expression in human breast MCF-7 cells exposed to drug vehicles-methanol and dimethyl sulfoxide (DMSO) for 24 hrs

BACKGROUND: Methanol and DMSO are commonly used as carrier solvents for lipophilic chemicals in in-vitro experiments. However, very little information is available regarding the effects of these solvents on the expression of pro and anti-apoptotic genes and proteins. MATERIALS AND METHODS: In this s...

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Detalles Bibliográficos
Autores principales: Adefolaju, Gbenga Anthony, Theron, Kathrine E, Hosie, Margot Jill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518331/
https://www.ncbi.nlm.nih.gov/pubmed/26229223
http://dx.doi.org/10.4103/0300-1652.160349