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miR-218 is Essential to Establish Motor Neuron Fate as a Downstream Effector of Isl1-Lhx3

While microRNAs have emerged as an important component of gene regulatory networks, it remains unclear how microRNAs collaborate with transcription factors in the gene networks that determines neuronal cell fate. Here, we show that in the developing spinal cord, the expression of miR-218 is directly...

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Detalles Bibliográficos
Autores principales: Thiebes, Karen P., Nam, Heejin, Cambronne, Xiaolu A., Shen, Rongkun, Glasgow, Stacey M., Cho, Hyong-Ho, Kwon, Ji-sun, Goodman, Richard H., Lee, Jae W., Lee, Seunghee, Lee, Soo-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518464/
https://www.ncbi.nlm.nih.gov/pubmed/26212498
http://dx.doi.org/10.1038/ncomms8718