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Inhibitory effect of Phyllanthus urinaria L. extract on the replication of lamivudine-resistant hepatitis B virus in vitro

BACKGROUND: Long-term treatment of chronic hepatitis B (CHB) with nucleos(t)ide analogs results in the emergence of drug-resistant hepatitis B virus (HBV) harboring mutations in the polymerase (P) gene. The Phyllanthus extract has anti-HBV activity; however, its antiviral activity against lamivudine...

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Detalles Bibliográficos
Autores principales: Jung, Jaesung, Kim, Nam Keun, Park, Sun, Shin, Ho-Joon, Hwang, Seong Gyu, Kim, Kyongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518506/
https://www.ncbi.nlm.nih.gov/pubmed/26220282
http://dx.doi.org/10.1186/s12906-015-0792-3