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Inhibitory effect of Phyllanthus urinaria L. extract on the replication of lamivudine-resistant hepatitis B virus in vitro

BACKGROUND: Long-term treatment of chronic hepatitis B (CHB) with nucleos(t)ide analogs results in the emergence of drug-resistant hepatitis B virus (HBV) harboring mutations in the polymerase (P) gene. The Phyllanthus extract has anti-HBV activity; however, its antiviral activity against lamivudine...

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Detalles Bibliográficos
Autores principales:	Jung, Jaesung, Kim, Nam Keun, Park, Sun, Shin, Ho-Joon, Hwang, Seong Gyu, Kim, Kyongmin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518506/ https://www.ncbi.nlm.nih.gov/pubmed/26220282 http://dx.doi.org/10.1186/s12906-015-0792-3

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