In vitro myotoxic effects of bupivacaine on rhabdomyosarcoma cells, immortalized and primary muscle cells

BACKGROUND: Rhabdomyosarcoma is a rare malignant skeletal muscle tumor. It mainly occurs in children and young adults and has an unsatisfactory prognosis. Prior studies showed a direct myotoxic effect of bupivacaine on differentiated muscle cells in vitro and in vivo. Exact mechanisms of this myotox...

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Detalles Bibliográficos
Autores principales: Metterlein, Thomas, Hoffmann, Petra, Späth, Ruth, Gruber, Michael, Graf, Bernhard M, Zink, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518519/
https://www.ncbi.nlm.nih.gov/pubmed/26225122
http://dx.doi.org/10.1186/s12935-015-0229-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518519/
https://www.ncbi.nlm.nih.gov/pubmed/26225122
http://dx.doi.org/10.1186/s12935-015-0229-6

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