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In vitro myotoxic effects of bupivacaine on rhabdomyosarcoma cells, immortalized and primary muscle cells
BACKGROUND: Rhabdomyosarcoma is a rare malignant skeletal muscle tumor. It mainly occurs in children and young adults and has an unsatisfactory prognosis. Prior studies showed a direct myotoxic effect of bupivacaine on differentiated muscle cells in vitro and in vivo. Exact mechanisms of this myotox...
Autores principales: | Metterlein, Thomas, Hoffmann, Petra, Späth, Ruth, Gruber, Michael, Graf, Bernhard M, Zink, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518519/ https://www.ncbi.nlm.nih.gov/pubmed/26225122 http://dx.doi.org/10.1186/s12935-015-0229-6 |
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