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Decreased VEGF-A and sustained PEDF expression in a human retinal pigment epithelium cell line cultured under hypothermia

BACKGROUND: Previous reports have described a decrease in retinal temperature and clinical improvement of wet age-related macular degeneration (AMD) after vitrectomy. We hypothesized that the retinal temperature decrease after vitrectomy plays a part in the suppression of wet AMD development. To tes...

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Detalles Bibliográficos
Autores principales: Takeyama, Masayuki, Yoneda, Masahiko, Gosho, Masahiko, Iwaki, Masayoshi, Zako, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518530/
https://www.ncbi.nlm.nih.gov/pubmed/26223306
http://dx.doi.org/10.1186/s40659-015-0034-7