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Inhibition of CDK4/6 as a novel therapeutic option for neuroblastoma
BACKGROUND: Neuroblastoma is a neural crest-derived tumor and is the most common cancer in children less than 1 year of age. We hypothesized that aberrations in genes that control the cell cycle could play an important role in the pathogenesis of neuroblastoma and could provide a tractable therapeut...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518532/ https://www.ncbi.nlm.nih.gov/pubmed/26225123 http://dx.doi.org/10.1186/s12935-015-0224-y |