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Inhibition of CDK4/6 as a novel therapeutic option for neuroblastoma

BACKGROUND: Neuroblastoma is a neural crest-derived tumor and is the most common cancer in children less than 1 year of age. We hypothesized that aberrations in genes that control the cell cycle could play an important role in the pathogenesis of neuroblastoma and could provide a tractable therapeut...

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Detalles Bibliográficos
Autores principales:	Rihani, Ali, Vandesompele, Jo, Speleman, Frank, Van Maerken, Tom
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518532/ https://www.ncbi.nlm.nih.gov/pubmed/26225123 http://dx.doi.org/10.1186/s12935-015-0224-y

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