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Activated regulatory T cells suppress effector NK cell responses by an IL-2-mediated mechanism during an acute retroviral infection

BACKGROUND: It is well established that effector T cell responses are crucial for the control of most virus infections, but they are often tightly controlled by regulatory T cells (Treg) to minimize immunopathology. NK cells also contribute to virus control but it is not known if their antiviral eff...

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Detalles Bibliográficos
Autores principales: Littwitz-Salomon, Elisabeth, Akhmetzyanova, Ilseyar, Vallet, Cecilia, Francois, Sandra, Dittmer, Ulf, Gibbert, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518534/
https://www.ncbi.nlm.nih.gov/pubmed/26220086
http://dx.doi.org/10.1186/s12977-015-0191-3