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Direct conversion of human fibroblasts to induced serotonergic neurons

Serotonergic (5HT) neurons exert diverse and widespread functions in the brain. Dysfunction of the serotonergic system gives rise to a variety of mental illnesses including depression, anxiety, obsessive compulsive disorder, autism and eating disorders. Here we show that human primary fibroblasts we...

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Detalles Bibliográficos
Autores principales: Xu, Z, Jiang, H, Zhong, P, Yan, Z, Chen, S, Feng, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518549/
https://www.ncbi.nlm.nih.gov/pubmed/26216300
http://dx.doi.org/10.1038/mp.2015.101