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Evaluation of variant detection software for pooled next-generation sequence data

BACKGROUND: Despite the tremendous drop in the cost of nucleotide sequencing in recent years, many research projects still utilize sequencing of pools containing multiple samples for the detection of sequence variants as a cost saving measure. Various software tools exist to analyze these pooled seq...

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Detalles Bibliográficos
Autores principales: Huang, Howard W., Mullikin, James C., Hansen, Nancy F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518579/
https://www.ncbi.nlm.nih.gov/pubmed/26220471
http://dx.doi.org/10.1186/s12859-015-0624-y