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FGF21 protects against ox-LDL induced apoptosis through suppressing CHOP expression in THP1 macrophage derived foam cells

BACKGROUND: FGF21,as a member of the fibroblast growth factor superfamily, is an important endogenous regulator to systemic glucose and lipid metabolism. Elevated serum FGF21 levels have been reported in subjects with coronary heart disease and carotid artery plaques. The formation and apoptosis of...

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Detalles Bibliográficos
Autores principales: Li, En, Wang, Ting, Wang, Feng, Wang, Tao, Sun, Li-qiang, Li, Li, Niu, Shao-hui, Zhang, Jin-ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518604/
https://www.ncbi.nlm.nih.gov/pubmed/26223891
http://dx.doi.org/10.1186/s12872-015-0077-2